Atypical Symptoms on Admission Predict Progression to Heart Failure in Patients With First-Time Myocardial...

Area of Science:

• Cardiology
• Clinical Research

Background:

• Myocardial infarction (MI) is a primary cause of heart failure (HF).
• Predicting HF progression post-MI is essential for patient management.

Purpose of the Study:

• To identify predictors of rehospitalization due to HF in patients experiencing their first MI.
• Utilized data from the Korea Acute Myocardial Infarction Registry-National Institutes of Health (KAMIR-NIH) prospective cohort (2011-2015).

Main Methods:

• Secondary data analysis of 8888 patients with 3-year follow-up.
• Propensity score matching (1:4) on 11 baseline characteristics.
• Comparison of clinical conditions and complications between HF (n=252) and non-HF (n=991) groups.

Main Results:

• Dyspnea (HR, 1.54), left ventricular ejection fraction <50% (HR, 2.71), and new-onset HF during hospitalization (HR, 1.77) predicted HF rehospitalization.
• Atypical chest pain was only significant in univariate analysis.

Conclusions:

• Post-MI patients require vigilant outpatient monitoring for HF progression.
• Patients presenting with dyspnea or developing new-onset HF during hospitalization are high-risk for HF rehospitalization.