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Risks and Benefits of Cervical Transforaminal Epidural Steroid Injections: A Comprehensive Review
Jamal Hasoon1, Ashlyn Brown2, Alexandra Moauro3
1Department of Anesthesiology, Critical Care, and Pain Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA. Jamal.J.Hasoon@uth.tmc.edu.
Current Pain and Headache Reports
|April 2, 2025
Summary
Cervical transforaminal epidural steroid injections (CTFESIs) offer pain relief and functional improvement for cervical radiculopathy. Careful patient selection and advanced techniques are vital to mitigate rare but severe risks.
Area of Science:
- Interventional Pain Medicine
- Neurosurgery
- Radiology
Background:
- Cervical transforaminal epidural steroid injections (CTFESIs) are a common treatment for cervical radicular pain.
- Pathologies like disc herniations and foraminal stenosis necessitate effective pain management strategies.
Purpose of the Study:
- To analyze the risks and benefits of CTFESIs.
- To evaluate the efficacy and safety profile of CTFESIs.
- To enhance clinical decision-making for interventional pain physicians.
Main Methods:
- Comprehensive review of current literature on CTFESIs.
- Analysis of procedural techniques and safety protocols.
- Evaluation of patient selection criteria.
Main Results:
- CTFESIs provide significant pain relief and functional improvement, potentially avoiding surgery.
- Safety concerns exist due to cervical vascular proximity, with rare but severe complications possible.
- Advanced techniques like fluoroscopic guidance and non-particulate steroids are crucial for risk mitigation.
Conclusions:
- CTFESIs are a valuable tool for selected cervical radiculopathy patients.
- Careful patient selection and strict adherence to safety protocols are essential.
- This review aids clinicians in risk-benefit assessment for CTFESIs.

