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Updated: May 17, 2025
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Folding and Characterization of a Bio-responsive Robot from DNA Origami
Published on: December 3, 2015
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Targeting Bacterial Cells with DNA Nanostructures
1Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK.
Methods in Molecular Biology (Clifton, N.J.)
|April 2, 2025
Abstract:
DNA origami nanostructures offer wide potential for controlled functionalization with molecules of interest, such as peptides, enzymes, small-molecule drugs, and fluorophores. Here, we describe a protocol for the synthesis and characterization of aptamer-modified DNA origami nanostructures that can act as a vehicle for delivering antimicrobials to Gram-positive and Gram-negative bacterial targets in a specific and efficient manner.
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