Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Clearance Models: Noncompartmental Models01:17

Clearance Models: Noncompartmental Models

Clearance is a pharmacokinetic parameter traditionally defined by compartment models, signifying the rate at which a drug is expelled from the body. However, a noncompartmental model offers an alternative method for assessing clearance, primarily employing empirical data obtained after administering a single drug dose.
The noncompartmental approach capitalizes on extensive sampling data, correlating the volume of distribution to systemic exposure and the administered dosage. This method enables...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Transperitoneal laparoscopic excision of a giant adrenal lymphangioma: a step-by-step approach.

International journal of surgery case reports·2026
Same author

Multivariable model integrating PHI and mpMRI for detecting csPCa in biopsy-naïve men.

BJUI compass·2025
Same author

A new era in radical nephrectomy: Balancing innovation, training, and cost.

Scottish medical journal·2025
Same author

The state of robotic surgery in Spain: Results of a national survey on robotic surgery.

Scottish medical journal·2024
Same author

Robotic surgery for locally advanced T4 rectal cancer: feasibility and oncological quality.

Updates in surgery·2023
Same author

Arterial Fistulas in Urinary Diverted Patients: A Report of 5 Cases.

Cardiovascular and interventional radiology·2022

Related Experiment Video

Updated: Jun 22, 2026

Single Port Donor Nephrectomy
07:17

Single Port Donor Nephrectomy

Published on: March 12, 2011

50.5K

Validation of a Pulsatile Model for Laparoscopic Partial Nephrectomy: NEFPAR Model.

Jose Antonio Campos Sañudo1, Saul Higuera Pardo2, Roberto Ballestero Diego3

  • 1Department of Urology, Dr. Sulaiman Al Habib Medical Group, Ar Rayyan Hospital, Riyhad, Saudi Arabia.

Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
|April 3, 2025
PubMed
Summary

The NEFPAR pulsatile model offers a realistic, ethical, and cost-effective alternative for training in laparoscopic partial nephrectomy, particularly for simulating surgical bleeding. This nonliving simulation tool shows strong potential for urology training programs.

Keywords:
animal experimentationlaparoscopic partial nephrectomysimulation

More Related Videos

Robot-Assisted Kidney Transplantation
07:30

Robot-Assisted Kidney Transplantation

Published on: July 19, 2021

3.4K
5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats
05:34

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

Published on: April 4, 2025

421

Related Experiment Videos

Last Updated: Jun 22, 2026

Single Port Donor Nephrectomy
07:17

Single Port Donor Nephrectomy

Published on: March 12, 2011

50.5K
Robot-Assisted Kidney Transplantation
07:30

Robot-Assisted Kidney Transplantation

Published on: July 19, 2021

3.4K
5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats
05:34

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

Published on: April 4, 2025

421

Area of Science:

  • Urology
  • Surgical Simulation
  • Medical Education

Background:

  • Laparoscopic and robotic-assisted partial nephrectomy are standard treatments for small renal tumors.
  • Ethical and regulatory considerations necessitate alternatives to animal models for surgical training.
  • The NEFPAR pulsatile model was developed as a nonliving simulation for partial nephrectomy.

Purpose of the Study:

  • To validate the NEFPAR pulsatile model as a realistic and effective training tool for laparoscopic partial nephrectomy.
  • To assess participant perception of the model's realism, educational impact, and comparison to existing simulation methods.
  • To evaluate the model's potential for integration into urology training curricula.

Main Methods:

  • The NEFPAR model was constructed using porcine tissue, a pulsatile pump, and standard laparoscopic instruments.
  • Eleven participants (4 urologists, 7 residents) performed simulated laparoscopic partial nephrectomies.
  • Performance and perceptions were evaluated via survey, with data analyzed using Fisher's exact test (P < .05).

Main Results:

  • 72.7% of participants found the NEFPAR model realistic for key steps like tumor resection and hilum dissection.
  • 100% of participants highlighted the essential educational value of the simulated bleeding component.
  • The NEFPAR model surpassed nonpulsatile animal models in simulating bleeding and was comparable to cadaveric models in appearance and texture.

Conclusions:

  • The NEFPAR model effectively simulates critical aspects of laparoscopic partial nephrectomy, providing an ethical and cost-effective training solution.
  • The model is highly valued for its educational benefits, especially in replicating surgical bleeding.
  • Further refinements could enhance tissue consistency and tumor placement, supporting its integration into urology training to improve skills and reduce animal use.