Adult-Onset Eccrine Angiomatous Hamartoma Associated with Lower Extremity Venous Insufficiency: A Case Report

Eccrine angiomatous hamartoma (EAH) is a benign tumor characterized by the proliferation of eccrine glands and vascular structures. It can be congenital or appear during childhood, with rare cases arising in adults. EAH typically presents as a solitary purplish plaque or nodule but a multifocal presentation in a blaschkoid or segmental distribution has been described.

We report the case of an extensive EAH following the territory of the superficial veins of the lower limbs, arising in an adult diagnosed with venous insufficiency at a young age and that worsened after saphenectomy.

The histopathological and ultrasonographic characteristics suggest that this case may represent a new instance of EAH associated with arteriovenous malformation. We hypothesize that there might be common molecular pathways linking both conditions and that, in predisposed patients, saphenectomy can exacerbate EAH.