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Updated: May 16, 2025

Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
Electrochemical Cyclization of 2,3-Allenols
Wenyao Li1, Dong Huang1, Zhuowei Xu1
1Research Center for Molecular Recognition and Synthesis, Department of Chemistry, Fudan University, Shanghai 200433, P. R. China.
Abstract:
An efficient electrochemical bromocyclization of allenols has been realized for the synthesis of spirocyclic 2,5-dihydrofurans. The reaction used commercially available and nontoxic KBr as the brominating source in a simple setup under open-air conditions. Notably, optically active products can be obtained from optically active 2,3-allenols without any racemization, further enhancing the synthetic utility.
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