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Updated: Jun 18, 2026

In Vitro Model of Physiological and Pathological Blood Flow with Application to Investigations of Vascular Cell Remodeling
Published on: November 3, 2015
Impeller Position in a Magnetically Levitated Rotodynamic Blood Pump and Its Impact on In-Silico Hemocompatibility
Marko Grujic1, Rosmarie Schoefbeck1, Bente Thamsen1
1From the Christian Doppler Laboratory for Mechanical Circulatory Support, Department of Cardiac Surgery, Medical University of Vienna, Vienna, Austria.
The impeller position in HeartMate 3 blood pumps shifts significantly across operating conditions. While minor for overall pump function, impeller displacement can alter local flow dynamics, impacting hemocompatibility.
Area of Science:
- Biomedical Engineering
- Cardiovascular Devices
- Fluid Dynamics
Background:
- Impeller position in rotodynamic blood pumps (RPBs) is critical, influenced by electromagnetic and fluid forces.
- Understanding HeartMate 3 impeller dynamics is key for assessing hemocompatibility.
Purpose of the Study:
- To map the three-dimensional impeller position of the HeartMate 3 across various operating conditions.
- To evaluate the hemocompatibility implications of impeller displacement using computational fluid dynamics (CFD).
Main Methods:
- Utilized a transparent HeartMate 3 casing, laser distance measurements, and high-speed videography to capture impeller positions.
- Performed CFD simulations comparing displaced and centered impeller scenarios at a representative operating point.
Main Results:
- Impeller axial displacement reached 223 µm at 7 L/min and 7,000 rpm; radial displacement was up to 145 µm at 0 L/min and 7,000 rpm.
- CFD analysis showed impeller displacement caused <2% change in global pump parameters but up to 9% deviation in local flow metrics.
Conclusions:
- Impeller position in the HeartMate 3 varies considerably with operating parameters.
- Impeller displacement has a minor effect on overall pump performance but can influence local hemocompatibility, warranting further investigation.
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