Zero-dose children in Latin America: analysis of the problem and possible solutions

Maria L Avila-Aguero1,2,3, Helena Brenes-Chacon3, Mario Melgar4

  • 1Latin American Society of Pediatric Infectious Diseases, San Jose, Costa Rica.

F1000Research
|April 4, 2025
PubMed

Insights

Millions of zero-dose children (ZDC) in Latin America lack routine immunizations, increasing risks of vaccine-preventable diseases. Targeted communication and data strategies are crucial to improve vaccination coverage for these vulnerable populations.

Area of Science:

  • Pediatric Infectious Diseases
  • Public Health
  • Immunization Programs

Background:

  • Zero-dose children (ZDC) are defined as those never reached by routine immunization services.
  • Latin America has nearly 2.7 million infants under one with incomplete vaccination schedules.
  • Increased global incidence of vaccine-preventable diseases like measles and polio is a concern.

Purpose of the Study:

  • To analyze the global and regional reality of ZDC in Latin America.
  • To present an updated situation of ZDC in the Latin American region.
  • To identify potential interventions to improve immunization coverage.

Main Methods:

  • Expert analysis by the Latin America Society of Pediatric Infectious Diseases (SLIPE) in November 2023.
  • Review of global and regional data on ZDC.
  • Assessment of intervention strategies for vaccination coverage.

Main Results:

  • ZDC are concentrated in high-risk settings such as remote-rural areas, urban slums, and conflict zones.
  • Effective communication strategies, including targeted messaging and community education, are vital.
  • Improved quality and utilization of vaccination data can prevent missed vaccination opportunities.

Conclusions:

  • Addressing the ZDC issue requires country-specific identification of problems and settings.
  • Inter-sectoral coordination and community engagement are essential for improving immunization coverage.
  • Strategic communication campaigns can significantly enhance vaccination uptake and reduce disease incidence.
Abstract

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