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Surgical Management of Tumours Invading the Inferior Vena Cava: A Delphi Consensus Document
Peter Balaz1, Adam Whitley2, Ivika Heinola3
1Division of Vascular Surgery, Department of General Surgery, University Hospital Královské Vinohrady, Prague, Czech Republic; Cardiocentre, Third Faculty of Medicine, Charles University, Prague, Czech Republic.
Expert consensus was established for managing retroperitoneal tumors involving the inferior vena cava (IVC). Key recommendations include CT imaging, IVC reconstruction for suprarenal involvement, and specific thrombectomy or resection strategies for IVC malignancy.
Area of Science:
- Vascular Surgery
- Surgical Oncology
- Medical Imaging
Background:
- Retroperitoneal malignancy involving the inferior vena cava (IVC) presents treatment challenges due to limited data and inconsistent management strategies.
- Establishing expert consensus is crucial for guiding surgical decisions in these complex cases.
Purpose of the Study:
- To establish an expert consensus on the surgical management of retroperitoneal tumors that involve the inferior vena cava (IVC).
Main Methods:
- A three-round Delphi project involving fourteen surgical experts.
- Data collection occurred between January 1, 2023, and December 15, 2023.
- Consensus was defined as 70% agreement, with statistical validation using Cronbach's α (0.05).
Main Results:
- Abdominal computed tomography (CT) is the gold standard for assessing IVC tumor invasion; CT-guided core needle biopsy is preferred for tissue diagnosis.
- Suprarenal IVC should be reconstructed, but not if chronically occluded with collateral circulation.
- Malignant thrombi without vessel wall involvement warrant thrombectomy; otherwise, IVC resection is recommended, preferably with an expanded polytetrafluoroethylene (ePTFE) prosthesis.
- IVC filters and arteriovenous fistulas are not recommended. Post-operative care includes therapeutic heparinization, mechanical compression, and routine CT angiography.
Conclusions:
- This expert consensus provides guidance for clinicians managing retroperitoneal tumors involving the IVC.
- The recommendations are based on limited literature and international expert experience, aiming to improve decision-making processes.
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