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Severe Infections in Returning Travelers

Cayleigh Blumrick1

  • 1Division of Infectious Diseases, Department of Medicine, Macon and Joan Brock Virginia Health Sciences at Old Dominion University, 825 Fairfax Avenue, Norfolk, VA 23507, USA.

The Medical Clinics of North America
|April 4, 2025
PubMed

Insights

Travelers, especially to low-middle income countries, often return with severe illnesses like malaria and dengue. A standardized evaluation, including travel history and symptom timeline, is crucial for diagnosing travel-related infections.

Area of Science:

  • Global Health
  • Infectious Diseases
  • Travel Medicine

Background:

  • Globalization increases the risk of travel-related infections, with 43%-79% of travelers to low-middle income countries returning with severe illness.
  • Accurate diagnosis of infections in returning travelers is critical for public health.
  • Common travel-related infections include malaria, dengue, and enteric fever.

Purpose of the Study:

  • To emphasize the importance of a standardized approach in evaluating returning travelers.
  • To highlight the need for a broad differential diagnosis considering geographically specific risks.
  • To underscore the significance of detailed travel history and symptom timelines.

Main Methods:

  • Utilizing a standardized approach for traveler evaluation.
  • Conducting thorough travel history assessments.
  • Correlating symptoms with geographically specific infection risks.

Main Results:

  • A significant percentage of travelers to low-middle income countries contract severe illnesses.
  • Malaria, dengue, and enteric fever are frequently diagnosed among returning travelers.
  • A systematic evaluation aids in identifying potential travel-related diseases.

Conclusions:

  • Awareness of travel-related infections is essential in a globalized world.
  • Standardized traveler evaluation improves diagnostic accuracy.
  • Geographically specific risk assessment is key to managing travel-related illnesses.
Keywords:
DengueEnteric feverFever in returning travelerMalaria

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