Related Experiment Video
Updated: May 16, 2025

Whole-Mount Immunofluorescence Staining, Confocal Imaging and 3D Reconstruction of the Sinoatrial and Atrioventricular Node in the Mouse
Published on: December 22, 2020
Translational Anatomy of the Sinoatrial Node: Myoarchitecture and its Relevance for Catheter Ablation: Part II:
Alejandro Jiménez Restrepo1, Mansour Razminia2, Damián Sánchez Quintana3
1Florida Electrophysiology Associates, Atlantis, Florida, USA; University of Maryland School of Medicine, Baltimore, Maryland, USA.
Anatomy:
Clinical applications relevant to the sinoatrial node anatomy for interventional electrophysiology procedures are reviewed.
Pathology:
Inappropriate sinus tachycardia, atrial tachycardia, and superior vena cava triggers for atrial fibrillation.
Imaging Correlation:
Three-dimensional electroanatomic mapping, intracardiac echocardiography.
Treatment:
Ablation guided by activation mapping and intracardiac electrograms.
Take-Home Message:
Understanding the anatomy of the sinoatrial node and the perinodal region provides key anatomic concepts to safely and effectively guide ablation procedures.

