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Related Experiment Video

Updated: May 17, 2025

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Deep learning prediction of mammographic breast density using screening data.

Chen Chen1,2,3, Enyu Wang1,4, Vicky Yang Wang1,2

  • 1Taizhou Key Laboratory of Minimally Invasive Interventional Therapy & Artificial Intelligence, Taizhou Branch of Zhejiang Cancer Hospital (Taizhou Cancer Hospital), Taizhou, 317502, Zhejiang, China.

Scientific Reports
|April 4, 2025
PubMed
Summary

Deep learning models accurately assess mammographic breast density categories. The InceptionV3 model showed high performance, aiding radiologists in objective breast density quantification.

Keywords:
Automated breast density quantificationBreast cancer riskDeep learningMammography

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Area of Science:

  • Medical Imaging
  • Artificial Intelligence
  • Radiology

Background:

  • Mammographic breast density assessment is crucial for breast cancer risk stratification.
  • Objective and consistent breast density measurement remains a challenge.

Purpose of the Study:

  • To evaluate deep learning models for objective assessment of four mammographic breast density categories.
  • To compare the performance of deep learning models against radiologists.

Main Methods:

  • Retrospective analysis of 57,282 mammograms from 9,621 women.
  • Development and evaluation of four deep learning models, including InceptionV3.
  • Comparison of model performance using Average Precision (AP) and against radiologist assessments.

Main Results:

  • The InceptionV3 model achieved high AP values across all density categories (0.857-0.953).
  • InceptionV3 demonstrated superior accuracy and consistency compared to radiologists, especially in denser categories.
  • Radiologist performance decreased significantly in heterogeneously and extremely dense categories.

Conclusions:

  • Deep learning models, particularly InceptionV3, offer a valuable tool for objective quantification of mammographic breast density.
  • AI-assisted assessment can enhance diagnostic accuracy and consistency in mammography.