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Updated: May 17, 2025

Quantification of Diabetes-induced Adherent Leukocytes in Retinal Vasculature
Published on: January 24, 2025
Smoke-stack fluorescein leakage in a vitrectomised eye with proliferative diabetic retinopathy: a rare angiographic
Kanika Godani1, Vishma Prabhu1, Prathiba Hande1
1Dept. of Retina and Vitreous, Narayana Nethralaya, #121/C, 1st R Block, Chord Road, Rajaji Nagar, Bengaluru, 560010, Karnataka, India.
Background/Aim:
This case report aims to describe an unusual angiographic finding of smoke-stack leakage (SSL) in a vitrectomised eye of a patient with proliferative diabetic retinopathy (PDR).
Case Description:
A 59-year-old male with a 17-year history of type 2 diabetes mellitus underwent fundus fluorescein angiography (FA) following vitrectomy for vitreous hemorrhage secondary to PDR. His visual acuity at the time of FA was 6/6 in both eyes. The examination focused on identifying neovascularization elsewhere (NVE) and analysing leakage patterns. FA revealed active NVEs in the left eye with late-phase leakage nasally and inferiorly to the optic disc, while the right eye exhibited a distinctive SSL pattern from residual proliferation. Interestingly, the leakage subsided in the late phase, leaving only staining of the residual fibrous tissue.
Conclusion:
The observed SSL in this vitrectomised eye underscores unique post-surgical dynamics of fluorescein diffusion. This case highlights the importance of recognizing altered leakage patterns in vitrectomised patients, which can impact the evaluation and management of retinal neovascularization in PDR.

