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Updated: May 23, 2025

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Robot-Assisted Kidney Transplantation
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Intraindividual Perception of Open versus Robot-Assisted Partial Nephrectomy (PERCEPTION Trial): An Important
Philipp Reimold1,2, Luisa Bourgeois3, Lia Klefenz3
1Department of Urology, Philipps-University Marburg, Marburg, Germany, reimold@uni-marburg.de.
Urologia Internationalis
|April 6, 2025
Summary
Patients undergoing robot-assisted partial nephrectomy (RAPN) reported better physical condition, quality of life, and scar satisfaction compared to open partial nephrectomy (OPN). This intraindividual comparison favored RAPN for overall patient experience.
Area of Science:
- Urology
- Surgical Oncology
- Patient-Reported Outcomes
Background:
- Previous trials showed no clear advantage of robot-assisted partial nephrectomy (RAPN) over open partial nephrectomy (OPN).
- Clinical observations suggested potential patient benefits with RAPN.
- This study focused on intraindividual patient perceptions of both surgical approaches.
Purpose of the Study:
- To compare patient experiences and perceptions of open partial nephrectomy (OPN) versus robot-assisted partial nephrectomy (RAPN).
- To evaluate intraindividual outcomes following both surgical techniques for bilateral renal tumors.
Main Methods:
- Retrospective analysis of patient-reported outcome measures and scar assessment.
- Questionnaires completed for postoperative day 5 after OPN and RAPN, and date of presentation as reference.
Main Results:
- Open partial nephrectomy (OPN) was associated with longer hospitalization and ischemia times.
- Robot-assisted partial nephrectomy (RAPN) group reported better physical condition, quality of life, and scar satisfaction.
- Patients reported higher stress, depression, and anxiety after OPN and favored RAPN in direct comparison.
Conclusions:
- This study is the first to assess intraindividual perceptions of OPN vs. RAPN.
- Findings indicate a clear patient preference for robot-assisted partial nephrectomy (RAPN).
- The APPROACH trial was designed to further compare OPN and RAPN in routine care.
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