Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Heart Valves

Heart Valves

The human heart is a complex organ with an intricate system of valves that regulate blood flow. There are two main types of valves: atrioventricular (AV) valves and semilunar valves.
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Preoperative Intestinal Preconditioning to Prevent Postoperative Vasoplegia After Tricuspid Valve Surgery.

Annals of thoracic surgery short reports·2026

Same author

Improvement in left atrial strain after percutaneous mitral valvuloplasty is an independent prognostic marker in patients with rheumatic mitral stenosis.

Frontiers in cardiovascular medicine·2026

Same author

Prognostic significance of right ventricular-pulmonary artery coupling in patients undergoing tricuspid valve surgery.

Annals of cardiothoracic surgery·2026

Same author

Ten-Year Outcomes of Off-Pump Coronary Revascularization Using Bilateral Internal Mammary Arteries versus Hybrid Coronary Revascularization.

The Thoracic and cardiovascular surgeon·2026

Same author

Intestinal Tissue Damage Reduction After Distal Perfusion for Aortic Arch Surgery in a Neonatal Porcine Model.

Biomedicines·2026

Same author

Long-term left ventricular assist device support reinforces detrimental immunological effects.

Frontiers in immunology·2026

Search research articles

Related Experiment Video

Updated: May 16, 2025

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair

Published on: October 16, 2021

Arrhythmic Mitral Valve Prolapse: Pathophysiology, Diagnostics, and Management Strategies.

Jagdip Kang¹, Antonia van Kampen², Maja-Theresa Dieterlen²

¹University Department of Cardiac Surgery, Heart Center Leipzig, Leipzig, Germany; Division of Cardiac Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

Seminars in Thoracic and Cardiovascular Surgery

|April 6, 2025

Summary

This summary is machine-generated.

Mitral valve prolapse (MVP) can present with dangerous heart rhythm problems. This review covers MVP

Keywords:

arrhythmic mitral valve prolapse mitral valve mitral valve prolapse sudden cardiac death ventricular arrhythmia ventricular fibrosis

More Related Videos

An Image Guided Transapical Mitral Valve Leaflet Puncture Model of Controlled Volume Overload from Mitral Regurgitation in the Rat

An Image Guided Transapical Mitral Valve Leaflet Puncture Model of Controlled Volume Overload from Mitral Regurgitation in the Rat

Published on: May 19, 2020

Echocardiographic Approaches and Protocols for Comprehensive Phenotypic Characterization of Valvular Heart Disease in Mice

Echocardiographic Approaches and Protocols for Comprehensive Phenotypic Characterization of Valvular Heart Disease in Mice

Published on: February 14, 2017

Related Experiment Videos

Last Updated: May 16, 2025

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair

Published on: October 16, 2021

An Image Guided Transapical Mitral Valve Leaflet Puncture Model of Controlled Volume Overload from Mitral Regurgitation in the Rat

An Image Guided Transapical Mitral Valve Leaflet Puncture Model of Controlled Volume Overload from Mitral Regurgitation in the Rat

Published on: May 19, 2020

Echocardiographic Approaches and Protocols for Comprehensive Phenotypic Characterization of Valvular Heart Disease in Mice

Echocardiographic Approaches and Protocols for Comprehensive Phenotypic Characterization of Valvular Heart Disease in Mice

Published on: February 14, 2017

Area of Science:

Cardiology
Cardiac Electrophysiology

Background:

Mitral valve prolapse (MVP) is a common valvular heart condition.
MVP is associated with an elevated risk of ventricular arrhythmias and sudden cardiac death.
Arrhythmias can be the initial clinical manifestation of MVP.

Purpose of the Study:

To review the pathological mechanisms underlying ventricular arrhythmias in MVP.
To summarize current diagnostic strategies for MVP.
To discuss contemporary management approaches for MVP.

Main Methods:

Literature review of relevant studies on MVP, ventricular arrhythmias, diagnosis, and management.
Synthesis of evidence from preclinical and clinical research.
Analysis of current clinical guidelines and expert consensus.

Main Results:

Pathological mechanisms include valvular-related myocardial changes and neurohormonal activation.
Diagnostic tools include echocardiography and electrophysiological studies.
Management strategies range from observation to antiarrhythmic drugs and interventions.

Conclusions:

Understanding MVP's arrhythmogenic potential is crucial for risk stratification.
Early diagnosis and appropriate management can mitigate the risk of sudden cardiac death.
Further research is needed to refine risk prediction and treatment protocols.