Recent advances in 3D printing applications for CNS tumours

Area of Science:

• Neurosurgery
• Oncology
• Medical Technology

Background:

• Three-dimensional printing (3DP) is revolutionizing central nervous system (CNS) tumor management.
• It enables precise replication of tumor microenvironments, vascularization, and genetic heterogeneity for personalized therapies.

Purpose of the Study:

• To review the advancements and challenges of 3DP in CNS tumor diagnosis, treatment, and education.
• To highlight 3DP's role in enhancing surgical planning, intraoperative guidance, and medical training.

Main Methods:

• Literature review of studies on 3DP applications in CNS tumors.
• Analysis of 3DP's impact on preoperative planning, surgical execution, and neurosurgical education.

Main Results:

• 3DP provides patient-specific models for improved tumor localization and surgical planning.
• Enhanced visualization and realistic simulations benefit neurosurgical training and patient education.
• 3DP facilitates the development of targeted therapies and personalized treatment strategies.

Conclusions:

• 3DP holds significant promise for improving CNS tumor care through enhanced precision and personalized approaches.
• Challenges including material biocompatibility, cost, and regulatory frameworks require further investigation.
• Continued research is crucial to optimize the clinical impact of 3DP in neuro-oncology.