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Updated: May 17, 2025

Author Spotlight: Decoding Corneal Neovascularization with Alkali Burn Model for Future Therapeutic Strategies
Published on: June 30, 2023
[Progress in the therapy of corneal neovascularization]
1The Third People's Hospital of Dalian Affiliated to Dalian Medical University, Dalian Municipal Eye Hospital, Liaoning Provincial Key Laboratory of Cornea and Ocular Surface Diseases, Liaoning Provincial Optometry Technology Engineering Research Center, Dalian 116033, China.
Abstract:
Corneal neovascularization, a severe pathologic change of the ocular surface, is usually caused by complex pathogeneses, and leads to severe vision damage and eventually corneal blindness. The applications of anti-inflammatory and anti-angiogenic drugs as well as keratoplasty have proved to have certain therapeutic effects. However, there are still numerous barriers that have not yet been fully overcome, prompting a trend towards treatment with multidisciplinary techniques. In this review, we summarize the latest research progress and give an overview of the techniques and strategies for treatment of corneal neovascularization in recent years based on the new mechanistic findings, aiming to improve the therapeutic efficiency and precision.

