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Updated: May 15, 2025

A Novel Bayesian Change-point Algorithm for Genome-wide Analysis of Diverse ChIPseq Data Types
Published on: December 10, 2012
Online Bayesian changepoint detection for network Poisson processes with community structure
Joshua Corneck1, Edward A K Cohen1, James S Martin1
1Department of Mathematics, Imperial College London, 180 Queen's Gate, London, SW7 2AZ UK.
Abstract:
Network point processes often exhibit latent structure that govern the behaviour of the sub-processes. It is not always reasonable to assume that this latent structure is static, and detecting when and how this driving structure changes is often of interest. In this paper, we introduce a novel online methodology for detecting changes within the latent structure of a network point process. We focus on block-homogeneous Poisson processes, where latent node memberships determine the rates of the edge processes. We propose a scalable variational procedure which can be applied on large networks in an online fashion via a Bayesian forgetting factor applied to sequential variational approximations to the posterior distribution. The proposed framework is tested on simulated and real-world data, and it rapidly and accurately detects changes to the latent edge process rates, and to the latent node group memberships, both in an online manner. In particular, in an application on the Santander Cycles bike-sharing network in central London, we detect changes within the network related to holiday periods and lockdown restrictions between 2019 and 2020.
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