Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Acute Coronary Syndrome I: Introduction

Acute Coronary Syndrome I: Introduction

Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...

Acute Coronary Syndrome IV: Interprofessional Care

Acute Coronary Syndrome IV: Interprofessional Care

IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...

Ischemic Stroke l: Introduction

Ischemic Stroke l: Introduction

Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.

Ischemic Stroke ll: Pathophysiology

Ischemic Stroke ll: Pathophysiology

An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...

Transient Ischemic Attack l: Introduction

Transient Ischemic Attack l: Introduction

A transient ischemic attack (TIA) is a brief episode of neurological dysfunction caused by a temporary, focal reduction in cerebral blood flow. Although symptoms resemble those of an ischemic stroke, the interruption in perfusion is short-lived and does not cause permanent infarction. TIAs are clinically important because they often serve as early warning events for future stroke.Mechanisms of Transient Cerebral IschemiaTransient cerebral ischemia may arise through several mechanisms. One...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Alternative vegetation states and limited reversibility: Insights from a novel grazing experiment.

The Science of the total environment·2026

Same author

Role of <i>NPR1</i> in Systemic Acquired Stomatal Immunity.

Plants (Basel, Switzerland)·2023

Same author

Knee Injuries Due to Blocking: A Continuing Problem.

The Physician and sportsmedicine·2017

Same author

A randomized trial of computerized vs. in-person brief intervention for illicit drug use in primary care: outcomes through 12 months.

Journal of substance abuse treatment·2014

Same author

Computerized versus in-person brief intervention for drug misuse: a randomized clinical trial.

Addiction (Abingdon, England)·2014

Same author

Implementing a statewide Screening, Brief Intervention, and Referral to Treatment (SBIRT) service in rural health settings: New Mexico SBIRT.

Substance abuse·2012

Search research articles

Related Experiment Video

Updated: May 12, 2026

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis

Published on: December 28, 2012

Synchronous Acute Ischemic Stroke and Acute Myocardial Infarction: A Case Report.

Ivan Grela¹, Thomas R Peterson^1,2

¹Emergency Medicine, Florida Atlantic University Charles E. Schmidt College of Medicine, Boca Raton, USA.

|April 7, 2025

Summary

Concurrent cardiocerebral infarction (CCI), a rare condition of simultaneous acute ischemic stroke (AIS) and acute myocardial infarction (AMI), requires careful management. This case highlights successful treatment balancing thrombolysis and dual antiplatelet therapy risks.

Keywords:

acute st-elevation myocardial infarction ais (acute ischemic stroke)cardiocerebral infarction emergency and acute care stroke management

More Related Videos

A Magnetic Resonance Imaging Protocol for Stroke Onset Time Estimation in Permanent Cerebral Ischemia

A Magnetic Resonance Imaging Protocol for Stroke Onset Time Estimation in Permanent Cerebral Ischemia

Published on: September 16, 2017

Author Spotlight: Assessing Ischemic Stroke Damage Through Middle Cerebral Artery Occlusion Model

Author Spotlight: Assessing Ischemic Stroke Damage Through Middle Cerebral Artery Occlusion Model

Published on: August 11, 2023

Related Experiment Videos

Last Updated: May 12, 2026

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis

Published on: December 28, 2012

A Magnetic Resonance Imaging Protocol for Stroke Onset Time Estimation in Permanent Cerebral Ischemia

A Magnetic Resonance Imaging Protocol for Stroke Onset Time Estimation in Permanent Cerebral Ischemia

Published on: September 16, 2017

Author Spotlight: Assessing Ischemic Stroke Damage Through Middle Cerebral Artery Occlusion Model

Author Spotlight: Assessing Ischemic Stroke Damage Through Middle Cerebral Artery Occlusion Model

Published on: August 11, 2023

Area of Science:

Cardiology
Neurology
Emergency Medicine

Background:

Concurrent cardiocerebral infarction (CCI) involves simultaneous acute ischemic stroke (AIS) and acute myocardial infarction (AMI).
CCI is a rare, life-threatening condition presenting diagnostic and therapeutic challenges.
Limited literature exists on managing patients with concurrent AIS and AMI.

Observation:

A 51-year-old male presented with symptoms of AIS (right-sided paralysis, aphasia) and an NIHSS score of 24.
Cerebral imaging revealed an occluded left internal carotid artery terminus.
EKG post-thrombectomy showed ST elevations, indicating acute myocardial infarction.

Findings:

The patient received tenecteplase and underwent successful mechanical thrombectomy for AIS.
Percutaneous coronary intervention with drug-eluting stent placement was performed for the AMI.
Dual antiplatelet therapy with aspirin and clopidogrel was administered post-procedure.

Implications:

Successful management of CCI requires a multidisciplinary, holistic approach.
Balancing the risks and benefits of thrombolysis and dual antiplatelet therapy is crucial.
This case emphasizes the need for updated guidelines for managing synchronous AIS and AMI.