Periapically Extruded Calcium Silicate Cements in Retreated Teeth: A Case Report and Literature Review

Calcium silicate-based materials, known for their bioactive properties, are increasingly being used in endodontic therapy. Accidental extrusion of these materials into the periapical tissue is a relatively common phenomenon that can impede periapical healing. The aim of this article is to present three endodontically retreated case reports with moderate to extensive periapical lesions and to review the literature on this topic. The comprehensive search and analysis of the relevant literature included a review of 51 articles, of which nine case reports/series from 2010 to 2023 were considered. Based on the summarized data, over 80% of the retreated cases showed complete healing of the periapical lesions, while the success rate in initially treated teeth was over 90%. Healing of periapical lesions is the most common therapeutic outcome, even in cases where extrusion occurs. Despite this conclusion, extrusion of materials into periapical tissues should be avoided. Further case reports on the extrusion of calcium silicate-based materials other than MTA are recommended. When evaluating the success rate of periapical healing in such cases, it is recommended to extend the follow-up periods to several years.