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Updated: May 15, 2025

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Unveiling Psoriasis: Delving into Pathogenesis, Treatment Breakthroughs, and Patent Trends.
Azad Kumar Maurya1, Dharmendra Jain1
1Department of Pharmaceutical Sciences, Dr. Harisingh Gour Vishwavidyalaya, Sagar (M.P.), Pin Code, 470003, India.
Psoriasis, a chronic inflammatory skin disease affecting millions, involves genetic and environmental factors. Research is advancing therapies from topicals to biologics and small molecules for better symptom control and patient outcomes.
Area of Science:
- Dermatology
- Immunology
- Genetics
Background:
- Psoriasis is a prevalent chronic inflammatory skin condition with significant patient impact.
- Its etiology is complex, involving genetic predisposition, immune system dysregulation, and environmental triggers.
Purpose of the Study:
- To provide a comprehensive review of psoriasis, covering its background, pathogenesis, and therapeutic evolution.
- To highlight recent advancements in treatment modalities and patent landscape.
Main Methods:
- Literature review of existing research and review articles.
- Synthesis of information on psoriasis prevalence, pathogenesis, and treatment history.
- Analysis of patent data for innovative therapeutic developments.
Main Results:
- Elucidation of the multifactorial pathogenesis of psoriasis, including immunological and genetic components.
- Overview of the evolution of psoriasis treatments, from traditional methods to modern biologics and small molecules.
- Identification of key advancements and future directions in psoriasis therapy through patent analysis.
Conclusions:
- Psoriasis management requires a multifaceted approach addressing its complex etiology.
- Ongoing research and patent activity indicate promising future therapeutic strategies for psoriasis.
- The review synthesizes current knowledge, offering insights into disease mechanisms and treatment innovations.
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