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Unlocking the antiviral arsenal: Structure-guided optimization of small-molecule inhibitors against RSV and hCoV-229E

Christina Karhan1, Svenja M Sake2, Antonia P Gunesch2

  • 1Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) - Helmholtz Centre for Infection Research (HZI), Campus Building E8.1, 66123, Saarbrücken, Germany; Saarland University, Department of Pharmacy, Campus Building E8.1, 66123, Saarbrücken, Germany.

European Journal of Medicinal Chemistry
|April 8, 2025
PubMed

Keywords:
RSV inhibitorsSARhCoV-229E inhibitorsselectivitysmall moleculesstructure-guided optimization

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