Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Thyroid Gland01:23

The Thyroid Gland

3.4K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
3.4K
Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

4.0K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
4.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Abdominal wall endometriosis in a caesarean section scar.

BMJ case reports·2026
Same author

Surgical management of umbilical endometrioma within an umbilical hernia.

BMJ case reports·2025
Same author

Early-stage serous fallopian tube carcinoma.

BMJ case reports·2023
Same author

Meigs syndrome presenting with severely elevated CA-125 level.

BMJ case reports·2021
Same author

Iatrogenic Cushing's Syndrome Following Intra-Articular Triamcinolone Injection in an HIV-Infected Patient on Cobicistat Presenting as a Pulmonary Embolism: Case Report and Literature Review.

International medical case reports journal·2020
Same author

Elevated circulating IGF-I promotes mammary gland development and proliferation.

Endocrinology·2010

Related Experiment Video

Updated: May 15, 2025

Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy
05:12

Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy

Published on: May 12, 2023

3.5K

Bilateral malignant struma ovarii with concurrent thyroid carcinoma.

Gwendolyn Glatz1, Danielle Lann2, Pritinder Thind3

  • 1Medical School, Hackensack Meridian Jersey Shore University Medical Center, Neptune, New Jersey, USA.

BMJ Case Reports
|April 8, 2025
PubMed
Summary

Malignant struma ovarii (MSO) with concurrent thyroid cancer is rare, lacking standard treatment. This case highlights surgical management and discusses controversial radioactive iodine therapy for MSO.

Keywords:
Endocrine cancerGynecological cancerObstetrics and gynaecology

More Related Videos

Transoral Robotic Total Thyroidectomy and Bilateral Central Regional Lymph Node Dissection for Papillary Thyroid Carcinoma
04:01

Transoral Robotic Total Thyroidectomy and Bilateral Central Regional Lymph Node Dissection for Papillary Thyroid Carcinoma

Published on: September 15, 2023

679
Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
03:55

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

Published on: June 9, 2023

465

Related Experiment Videos

Last Updated: May 15, 2025

Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy
05:12

Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy

Published on: May 12, 2023

3.5K
Transoral Robotic Total Thyroidectomy and Bilateral Central Regional Lymph Node Dissection for Papillary Thyroid Carcinoma
04:01

Transoral Robotic Total Thyroidectomy and Bilateral Central Regional Lymph Node Dissection for Papillary Thyroid Carcinoma

Published on: September 15, 2023

679
Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
03:55

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

Published on: June 9, 2023

465

Area of Science:

  • Gynecologic Oncology
  • Endocrinology
  • Pathology

Background:

  • Malignant struma ovarii (MSO) is a rare ovarian neoplasm.
  • The co-occurrence of MSO and thyroid carcinoma is exceptionally infrequent.
  • Established treatment protocols for this combined condition are lacking.

Purpose of the Study:

  • To report a case of a postmenopausal woman diagnosed with bilateral stage IA Malignant Struma Ovarii and concurrent papillary thyroid carcinoma.
  • To review and discuss the current literature on the management of MSO, particularly when associated with thyroid cancer.
  • To explore the controversial role of radioactive iodine therapy in MSO management.

Main Methods:

  • A case report of a postmenopausal woman presenting with symptoms suggestive of an adnexal mass.
  • Surgical intervention involving total laparoscopic hysterectomy and bilateral salpingo-oophorectomy.
  • Metastatic workup including evaluation for concurrent thyroid malignancy.
  • Comprehensive literature review on MSO and concurrent thyroid cancer treatment strategies.

Main Results:

  • The patient was diagnosed with bilateral stage IA Malignant Struma Ovarii and concurrent papillary thyroid carcinoma.
  • Surgical management included hysterectomy, bilateral salpingo-oophorectomy, total thyroidectomy, and neck dissection.
  • Adjuvant radioactive iodine therapy was administered for the thyroid carcinoma.
  • Literature review revealed varied treatment approaches for MSO, with a trend towards conservative management.

Conclusions:

  • Optimal treatment for Malignant Struma Ovarii concurrent with thyroid carcinoma remains debated.
  • While thyroid cancer management is more standardized, MSO treatment varies, with recent literature favoring conservative approaches.
  • The utility and controversy surrounding radioactive iodine therapy for MSO require further investigation and discussion.