[Stickler's syndrome or hereditary progressive arthro-ophthalmopathy]

Hereditary Progressive Arthro-Ophthalmopathy was described for the first time by Stickler. The major features of the syndrome are: myopia with retinal detachment and blindness, bone and joint dysplasia with arthropathy, and hearing loss. The condition is autosomal dominant with strong expressivity. Findings of 11 patients from 3 families are reported here: they confirm that this syndrome can be considered as a severe connective tissue disease.