Related Experiment Video
Updated: May 12, 2026
07:50
A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
Published on: September 20, 2018
15.7K
Guidelines for reporting artificial intelligence studies in medicines, pharmacotherapy, and pharmaceutical services:
Wallace Entringer Bottacin1, Thais Teles de Souza2, Walleri Christini Torelli Reis3
1Postgraduate Program in Pharmaceutical Services and Policies, Federal University of Paraná, Avenida Prefeito Lothário Meissner, 632 - Jardim Botânico, Curitiba, PR, CEP 80210-170, Brazil. wallace.bottacin@gmail.com.
International Journal of Clinical Pharmacy
|April 9, 2025
Summary
New MedinAI guidelines enhance transparency in artificial intelligence (AI) research for medicines and pharmaceutical services. These validated guidelines promote reproducible and ethical AI development in healthcare.
Area of Science:
- Pharmaceutical Sciences
- Medical Informatics
- Artificial Intelligence in Healthcare
Background:
- Expanding applications of artificial intelligence (AI) in medicines, pharmacotherapy, and pharmaceutical services.
- Lack of standardized reporting guidelines hinders transparency, comparability, and reproducibility in AI-driven healthcare research.
Purpose of the Study:
- To develop and validate comprehensive reporting guidelines for AI studies in medicines, pharmacotherapy, and pharmaceutical services.
- Establish standardized reporting to improve evidence-based healthcare decision-making.
Main Methods:
- Utilized a two-phase approach based on the Moher Guidance for Developers of Health Research Reporting Guidelines.
- Phase 1: Literature reviews and expert discussions for initial drafting.
- Phase 2: Delphi method with 26 international experts for validation and refinement, achieving consensus on items.
Main Results:
- Developed the MedinAI guidelines, comprising 14 items and 78 sub-items across four domains.
- Achieved high consensus (median=8, 95.2% agreement) for all items, indicating publication readiness.
- MedinAI guidelines are adaptable to various AI development stages and align with existing EQUATOR Network reporting standards.
Conclusions:
- MedinAI provides validated reporting guidelines for AI in medicines, pharmacotherapy, and pharmaceutical services.
- Promotes transparency, comparability, and reproducibility in AI research within these fields.
- Facilitates responsible and ethical AI development and application in healthcare.
Related Concept Videos
01:29Issues And Trends In Healthcare Delivery System
The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
01:16Clinical Trials
Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
There are four phases in a clinical trial. A phase one...
01:11Clinical Trials: Overview
Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
01:19Pharmacovigilance
Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
01:23Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...
01:26Therapeutic Drug Monitoring: Drug Analysis Methods
Therapeutic Drug Monitoring (TDM) is a clinical practice that measures specific drug levels in a patient's blood or body tissues to tailor drug therapy effectively. This monitoring is critical for managing drugs with narrow therapeutic indices like digoxin and phenytoin, ensuring they are both safe and effective. For instance, monitoring theophylline levels in asthma patients involves precision and sensitivity to adjust doses according to individual responses to therapy, ensuring efficacy and...