Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Histopathological and molecular heterogeneity of dysembryoplastic neuroepithelial tumors.

Journal of neuropathology and experimental neurology·2026
Same author

Forensic and neuropathological characteristics of lethal acute blunt traumatic spinal cord injury.

Journal of forensic sciences·2026
Same author

Temporal and cell-type specific SPAK-NKCC1 disruption following severe TBI in the developing gyrencephalic brain.

Acta neuropathologica communications·2026
Same author

Subgroup of meningiomas involving FOS and FOSB gene fusions.

Nature communications·2025
Same author

Pathological Calcium Signaling in Traumatic Brain Injury and Alzheimer's Disease: From Acute Neuronal Injury to Chronic Neurodegeneration.

International journal of molecular sciences·2025
Same author

DNA damage response profile distinguishes poor-acting gliomas with shared methylome signatures.

Neuro-oncology·2025
Same journal

Update on the molecular pathology of the distinctive giant cell, fibro-osseous and bone forming lesions of the jaws.

Seminars in diagnostic pathology·2026
Same journal

Update on the molecular pathology and classification of odontogenic cysts and tumours.

Seminars in diagnostic pathology·2026
Same journal

MDM2 gene amplification in surgical pathology: biology, diagnostic utility, and clinical relevance in the modern era.

Seminars in diagnostic pathology·2026
Same journal

When three negatives equal a positive: Molecular updates of triple-negative breast carcinomas with favorable prognoses.

Seminars in diagnostic pathology·2026
Same journal

Old school, new insight: Revisiting histomorphology in the modern era of prostate cancer risk stratification.

Seminars in diagnostic pathology·2026
Same journal

Recent advances in genetic predisposition to primary testicular tumors.

Seminars in diagnostic pathology·2026
See all related articles

Related Experiment Video

Updated: May 15, 2025

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping
13:12

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping

Published on: August 12, 2019

44.8K

Neuropathology Intraoperative Consultation.

Nalin Leelatian1, Declan McGuone2

  • 1Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.

Seminars in Diagnostic Pathology
|April 9, 2025
PubMed
Summary
This summary is machine-generated.

This review presents a diagnostic algorithm for intra-operative consultation (IOC) in neuropathology. It aims to improve specimen sampling and surgical guidance through clear communication and understanding of clinical findings.

Keywords:
Frozen sectionIntraoperative consultationNeuropathology

More Related Videos

Intra-Operative Behavioral Tasks in Awake Humans Undergoing Deep Brain Stimulation Surgery
12:04

Intra-Operative Behavioral Tasks in Awake Humans Undergoing Deep Brain Stimulation Surgery

Published on: January 6, 2011

12.9K
Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients
09:32

Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients

Published on: December 18, 2016

12.1K

Related Experiment Videos

Last Updated: May 15, 2025

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping
13:12

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping

Published on: August 12, 2019

44.8K
Intra-Operative Behavioral Tasks in Awake Humans Undergoing Deep Brain Stimulation Surgery
12:04

Intra-Operative Behavioral Tasks in Awake Humans Undergoing Deep Brain Stimulation Surgery

Published on: January 6, 2011

12.9K
Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients
09:32

Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients

Published on: December 18, 2016

12.1K

Area of Science:

  • Neuropathology
  • Surgical Pathology
  • Neurosurgery

Background:

  • Intra-operative consultation (IOC) in neuropathology is crucial for confirming specimen sampling and guiding surgical approaches.
  • Effective IOC relies on understanding clinical/imaging data and clear communication with neurosurgeons.
  • While neuropathologists often lead IOC, surgical pathologists may also provide this service, necessitating a structured approach.

Purpose of the Study:

  • To provide a diagnostic algorithm for neuropathology IOC.
  • To illustrate the algorithm's application using clinical case examples.
  • To enhance the quality of intra-operative neuropathology assessments.

Main Methods:

  • Development of a stepwise diagnostic algorithm for neuropathology IOC.
  • Inclusion of nine clinical vignettes to demonstrate algorithm utilization.
  • Discussion of pre-operative findings, differential diagnoses, and potential pitfalls.

Main Results:

  • The review outlines a systematic approach to neuropathology IOC.
  • Key findings for neurosurgical teams are identified for optimal specimen handling and surgical guidance.
  • The algorithm facilitates adequate tissue sampling for further studies.

Conclusions:

  • A structured diagnostic algorithm is valuable for neuropathology IOC, especially when provided by surgical pathologists.
  • Clear communication and integration of clinical/imaging data are essential for informative IOC.
  • This approach ensures optimal tissue adequacy for subsequent diagnostic and ancillary testing.