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Maintenance Haemodialysis in an LVAD Recipient in an Outpatient Community Dialysis Centre-A Case Report
Zheng Xi Kog1, Jiunn Wong1,2, Zhong Hong Liew1
1Department of Renal Medicine, Singapore General Hospital, Singapore, Singapore.
Insights
Managing patients with left ventricular assist devices (LVADs) who develop end-stage kidney disease (ESKD) requires a multidisciplinary approach. This case study highlights successful community hemodialysis transition for an LVAD recipient, emphasizing coordinated care.
Area of Science:
- Cardiology
- Nephrology
- Mechanical Circulatory Support
Background:
- Heart transplantation is limited by donor availability, increasing use of left ventricular assist devices (LVADs) for advanced heart failure.
- LVADs are increasingly used as destination therapy, especially for patients ineligible for heart transplantation.
- Acute kidney injury (AKI) is common post-LVAD, with survivors often developing chronic kidney disease (CKD) and end-stage kidney disease (ESKD).
Observation:
- There is a significant lack of guidance for managing LVAD recipients requiring long-term kidney replacement therapy (KRT), including hemodialysis.
- International guidelines for mechanical circulatory support (MCS) offer insufficient direction for these complex patients.
- A case of an LVAD patient developing ESKD after 2 years on support is presented, detailing the transition to community hemodialysis.
Findings:
- A multidisciplinary team (cardiothoracic surgery, cardiology, nephrology, LVAD coordinators, dialysis nurses) facilitated the patient's transition from inpatient to community care.
- Key considerations for managing LVAD recipients on maintenance hemodialysis in a community setting were identified and addressed.
- The successful transition demonstrates the feasibility of community-based KRT for LVAD patients.
Implications:
- Standardized, multidisciplinary care is essential for LVAD patients with renal impairment requiring KRT.
- Improved management protocols can ensure better post-operative care and enable community discharge for these patients.
- This approach can enhance the quality of life and long-term outcomes for an increasing population of LVAD recipients with kidney disease.
Abstract:
Heart transplant remains the treatment of choice for patients with advanced heart failure (HF). However, due to a lack of donor organs, left ventricular assist devices (LVADs) have been used as a bridge until donor organs become available. Recently, we have observed more patients with advanced HF being placed on LVAD as destination therapies, particularly in patients with contraindications to heart transplantation. Acute kidney injury (AKI) post-LVAD implantation is common. Even with renal recovery, these patients are surviving longer and hence it is not uncommon for them to eventually develop chronic kidney disease (CKD), potentially progressing to end-stage kidney disease (ESKD) requiring kidney replacement therapy (KRT). There remains a paucity of published literature to guide prescription and management of LVAD recipients on long-term maintenance KRT, particularly in the community setting. Even the latest international guidelines on mechanical circulatory support (MCS) fail to provide adequate guidance for the management of such patients. We present a case of a patient who was on LVAD for 2 years prior to developing ESKD and share our experience of transitioning her from an inpatient hospital setting to the community haemodialysis centre with the help of a multi-disciplinary care team consisting of the cardiothoracic surgeon, cardiologist, nephrologist, LVAD coordinators, and the community haemodialysis centre nursing team. We aim to share the considerations in management of LVAD recipients on maintenance haemodialysis in a community dialysis centre and how we cared for such a patient. With an increasing prevalence of LVAD patients with renal impairment potentially requiring KRT, a standardised multidisciplinary team approach will be essential to ensure better care for these patients in the immediate post-operative setting and offer these patients the option of eventual discharge to the community.
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