Related Experiment Video
Updated: May 5, 2026
06:36
An Ex vivo Model of an Oligodendrocyte-directed T-Cell Attack in Acute Brain Slices
Published on: February 5, 2015
6.9K
Primary central nervous system tumors in patients with multiple sclerosis
Masih Sabouri1, Masoud Etemadifar1, Fatemeh Dehghani Firoozabadi1
1Department of Neurosurgery, Alzahra University Hospital, Isfahan, Iran.
BMC Neurology
|April 9, 2025
Summary
The prevalence of central nervous system (CNS) tumors in multiple sclerosis (MS) patients is 1.58%, with pituitary adenomas and meningiomas being most common. Close monitoring for new symptoms is crucial due to potential overlap.
Area of Science:
- Neurology
- Oncology
Background:
- Multiple sclerosis (MS) shares diagnostic features with central nervous system (CNS) tumors.
- MS patients may have a higher risk of CNS malignancies despite a lower overall cancer risk.
Purpose of the Study:
- To investigate the prevalence of CNS tumors in patients diagnosed with MS.
- To identify common CNS tumor types in an MS population.
Main Methods:
- Cross-sectional observational study.
- Utilized data from the Isfahan MS clinic registry (2020-2023).
- Included MS patients diagnosed with primary CNS tumors post-MS diagnosis.
Main Results:
- Prevalence of CNS tumors in MS patients was 1.58% (36 of 2,280).
- Most common tumors: pituitary adenomas (41.7%) and meningiomas (30.6%).
- Mean age at tumor diagnosis was 45 years; mean age at MS diagnosis was 31.5 years.
Conclusions:
- The study found a 1.58% prevalence of primary CNS tumors in the studied MS population.
- Meningiomas and pituitary adenomas were the most frequent CNS tumors in MS patients.
- Emphasizes the need to assess new or atypical symptoms for potential CNS malignancies in MS patients.
Related Concept Videos
01:04Glial Cells
75.2K
Overview
75.2K
01:19Multiple Sclerosis l: Introduction
20
Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...
20