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Five Novel HLA-C Alleles Identified in Unrelated Bone Marrow Volunteers

Maria Loginova1,2, Igor Paramonov1

  • 1Federal State Budget Research Institution: Kirov Hematology and Blood Transfusion Research Institute Under the Federal Medicine and Biology Agency, Kirov, Russia.

HLA
|April 9, 2025
PubMed

Abstract:

Five novel HLA-C alleles have been identified using full next-generation sequencing.

Keywords:
HLA‐CNGSRussiannovel HLA allele

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Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
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