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Updated: May 15, 2025

Preparation of N-2-alkoxyvinylsulfonamides from N-tosyl-1,2,3-triazoles and Subsequent Conversion to Substituted Phthalans and Phenethylamines
Published on: January 3, 2018
Synthesis of thiopyran derivatives via [4 + 2] cycloaddition reactions
Maryam Mousavi-Ebadia1, Javad Safaei-Ghomi1, Masoumeh Jadidi Nejad2
1Department of Organic Chemistry, Faculty of Chemistry, University of Kashan Kashan 51167 I. R. Iran safaei@kashanu.ac.ir.
Abstract:
In this review, we provide a comprehensive overview of the synthesis of thiopyran family compounds via cycloaddition reactions, with examples spanning from the year 2000 to the present. We have categorized the [4 + 2] cycloaddition processes using several criteria, particularly distinguishing between intermolecular and intramolecular types based on the Diels-Alder partners. Additionally, from a mechanism standpoint, we differentiate between concerted and stepwise [4 + 2] processes, offering an analysis of these mechanisms based on the current literature.
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