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Updated: May 15, 2025

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy oSLO and Optical Coherence Tomography OCT

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy oSLO and Optical Coherence Tomography OCT

Published on: August 4, 2018

Visible-light optical coherence tomography and its applications.

Siyu Song^1,2, Tristan T Hormel¹, Yali Jia^1,2

¹Oregon Health and Science University, Casey Eye Institute, Portland, Oregon, United States.

|April 10, 2025

Summary

Visible-light optical coherence tomography (vis-OCT) offers high resolution and unique contrast for imaging. This review covers vis-OCT

Keywords:

brain imaging optical coherence tomography optical coherence tomography angiography retinal hemodynamics retinal imaging spectroscopic analysis

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Area of Science:

Biomedical optics
Medical imaging technology
Ophthalmology

Background:

Optical coherence tomography (OCT) traditionally uses near-infrared light.
Emerging visible-light OCT (vis-OCT) utilizes visible illumination.
Vis-OCT offers distinct advantages for specific imaging applications.

Purpose of the Study:

To review the development and applications of vis-OCT.
To highlight the capabilities of vis-OCT, including high resolution and oximetry.
To discuss challenges and future improvements for vis-OCT systems.

Main Methods:

Review of existing literature on vis-OCT.
Analysis of vis-OCT system implementation considerations.
Examination of demonstrated pre-clinical and clinical applications.

Main Results:

Vis-OCT achieves one-micron axial resolution.
Distinct scattering and absorption contrast enable oximetry.
Vis-OCT shows promise in various imaging scenarios.

Conclusions:

Vis-OCT is a valuable advancement in OCT technology.
Further development is needed to address implementation challenges.
Vis-OCT holds significant potential for future medical imaging.