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Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
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Updated: May 15, 2025

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Water Physical Exercise Program (WPEP) Using High-Intensity Interval Training in Individuals With Parkinson's

Luís Henrique Paladini1, Giovanna Cristina Leveck1, Tainá Christinelli1

  • 1Postgraduate Program in Physical Education, Federal University do Paraná, Curitiba, Paraná, Brazil.

Parkinson'S Disease
|April 10, 2025
PubMed
Summary

This study protocol outlines a 12-week high-intensity interval training (HIIT) water physical exercise program (WPEP) for Parkinson's disease (PD) patients. The WPEP aims to improve cardiorespiratory, motor, and nonmotor symptoms in early to moderate stage PD.

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Area of Science:

  • Neurology
  • Exercise Physiology
  • Rehabilitation Science

Background:

  • Parkinson's disease (PD) is a neurodegenerative disorder impacting CNS function.
  • PD complications include impaired cardiorespiratory capacity and motor/nonmotor symptoms.
  • High-intensity exercise in aquatic environments may mitigate PD symptoms.

Purpose of the Study:

  • To develop and evaluate a water physical exercise program (WPEP).
  • The WPEP will incorporate high-intensity interval training (HIIT) principles.
  • Target population: individuals with PD Stages 1-4 (Hoehn and Yahr scale).

Main Methods:

  • Protocol for a single-blinded controlled clinical trial.
  • Participants divided into a control group and a WPEP group.
  • WPEP intervention: 12 weeks, twice weekly, 35-min sessions, 48-72h recovery interval.

Main Results:

  • Outcomes assessed across cardiorespiratory, motor, and nonmotor domains.
  • Study aims to establish parameters for WPEP prescription and monitoring.
  • Expected to enhance exercise prescription for PD patients.

Conclusions:

  • The study protocol provides a framework for a novel WPEP for PD.
  • This research is expected to offer evidence-based guidelines for aquatic exercise in PD management.
  • The findings will contribute to optimizing physical activity interventions for individuals with early to moderate PD.