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Updated: May 15, 2025
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Cone Beam Intraoperative Computed Tomography-based Image Guidance for Minimally Invasive Transforaminal Interbody Fusion
Published on: August 6, 2019
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Distinct Recovery Patterns After Transforaminal Lumbar Interbody Fusion: Comparing Minimally Invasive and Open
Tomoyuki Asada1, Eric R Zhao1,2, Adin M Ehrlich1
1Hospital for Special Surgery, New York, NY, USA.
Neurospine
|April 11, 2025
Summary
Minimally invasive-transforaminal lumbar interbody fusion (MIS-TLIF) leads to faster recovery and earlier pain relief compared to open TLIF. Patients undergoing MIS-TLIF experienced less disability in the first two weeks and earlier back pain resolution.
Area of Science:
- Spine surgery
- Orthopedics
- Neurosurgery
Background:
- Minimally invasive-transforaminal lumbar interbody fusion (MIS-TLIF) offers clinical advantages over open approaches.
- Limited evidence exists on patient-reported outcomes and recovery trajectories for MIS-TLIF versus open TLIF.
Purpose of the Study:
- To compare postoperative recovery trajectories and symptomatic improvement phases between MIS-TLIF and open TLIF.
- To evaluate patient-reported outcomes including disability and pain levels.
Main Methods:
- Retrospective review of patients undergoing single-level MIS or open TLIF.
- Collected Oswestry Disability Index (ODI) and Numerical Rating Scale (NRS) for pain pre- and postoperatively.
- Utilized segmented regression analysis with mixed-effects modeling to analyze recovery phases.
Main Results:
- The MIS-TLIF group showed significantly lower disability exacerbation in the early postoperative phase (days 0-13).
- Back pain (NRS) reached a plateau significantly earlier in the MIS-TLIF group (approx. 4 weeks) compared to the open group.
- Baseline demographics were similar, though the MIS group had greater preoperative leg pain.
Conclusions:
- MIS-TLIF demonstrates superior early recovery, with reduced postoperative disability in the initial two weeks.
- The MIS approach facilitates an earlier resolution of low back pain compared to open TLIF.
