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Wearable Sensors for Physiological Condition and Activity Monitoring.

Pillalamarri Srikrishnarka1, Joonas Haapasalo2, Juan P Hinestroza3

  • 1Faculty of Engineering and Natural Sciences Korkeakoulunkatu 6 FI-33720 Tampere Finland.

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Summary

Wearable sensors can now noninvasively monitor health biomarkers in biofluids like sweat and tears. This review analyzes advancements in wearable metabolite sensors for real-time health tracking and theranostic applications.

Keywords:
biomarkerscondition monitoringsmetaboliteswearable sensors

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Area of Science:

  • Biomedical Engineering
  • Analytical Chemistry
  • Wearable Technology

Background:

  • Healthcare is shifting towards personalized management, driven by technological advancements.
  • Biofluids (teardrops, sweat, interstitial fluid, breath condensate) contain valuable biomarkers similar to blood.
  • Noninvasive metabolite detection via sensors offers an alternative to traditional blood tests.

Purpose of the Study:

  • To review recent progress in wearable sensors for monitoring metabolites in various biofluids.
  • To discuss methods for selective, real-time detection and quantification of metabolites.
  • To explore the potential of multifunctional sensors for theranostic applications.

Main Methods:

  • Analysis of recent literature on wearable sensors for biofluid metabolite monitoring.
  • Discussion of sensing mechanisms for selective metabolite detection.
  • Examination of sensor integration for combined monitoring and drug delivery.

Main Results:

  • Wearable sensors are advancing for real-time metabolite analysis in teardrops, sweat, breath condensate, and interstitial fluids.
  • Progress has been made in selective detection and quantification of key metabolites.
  • Multifunctional sensors integrating metabolite sensing, activity monitoring, and drug delivery are emerging.

Conclusions:

  • Wearable metabolite sensors are crucial for noninvasive, real-time health diagnostics.
  • Further development is needed for accurate and reliable metabolite monitoring.
  • Multifunctional wearable devices hold promise for integrated health management and theranostics.