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Updated: May 15, 2025

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Published on: December 20, 2024
Proximal bowel obstruction caused by high-grade duodenal adenocarcinoma: A rare case
Rana Ibrahim1, Mohammad Yassine2, Zakaria Dika3
1Research Department at Saint George Hospital-Hadath.
Introduction:
Duodenal adenocarcinoma is an exceptionally rare malignancy, constituting less than 0.5% of all gastrointestinal cancers. Its nonspecific symptoms often lead to delayed diagnosis and advanced disease at presentation.
Case Presentation:
A 64-year-old female presented with epigastric pain, nausea, and biliary vomiting. Imaging revealed a proximal small bowel obstruction, and endoscopy identified a high-grade duodenal adenocarcinoma. The patient underwent a successful duodenojejunectomy, side-to-side anastomosis, and lymphadenectomy.
Discussion:
Post-operative recovery was uneventful, leading to discharge in stable condition. This case underscores the importance of considering duodenal adenocarcinoma in differential diagnoses for small bowel obstruction and highlights the effectiveness of surgical management.
Conclusion:
Duodenal adenocarcinoma, though rare, should be considered in patients with small bowel obstruction. Early diagnosis and prompt surgical intervention are crucial for favorable outcomes.

