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Isolated Hypogonadotropic Hypogonadism in a Young Woman with Primary Amenorrhoea
Zalkha Al Kharusi1, Nadia Al Mabaihsi1, Amani Al Rawahi2
1Department of Primary Healthcare, Directorate General of Primary Healthcare, Ministry of Health, Muscat, Oman.
Abstract:
We describe a case of a young woman who presented with delayed secondary sexual development and primary amenorrhoea. She had low levels of oestradiol, follicle-stimulating hormone, and luteinizing hormone with normal levels of other pituitary hormones. Genetic testing revealed a rare diagnosis of autosomal recessive hypogonadotropic hypogonadism 8. She was treated with hormone therapy to promote the growth of the uterus and secondary sexual characteristics. Combined contraceptive pills were initiated. A pelvis ultrasound taken after six months revealed a growing uterus.
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