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Updated: May 14, 2025

A Murine Model of a Burn Wound Reconstructed with an Allogeneic Skin Graft
Published on: August 8, 2020
Post-Mohs surgical wounds treated with intact fish skin graft: a multicenter analysis
Ryan O'Quinn1, Courtney Aldridge1, David S Sax2
1South Texas Skin Cancer Center, San Antonio, TX, USA.
Background:
Intact fish skin graft (IFSG) has been reported to be an adjunct to healing post-Mohs surgical wounds.
Objective:
To assess the data that could be found on the use of IFSG in conjunction with Mohs surgery.
Materials And Methods:
A non-interventional observational registry collected data on the use, indications, and outcomes of IFSG over 32 weeks. This registry collected data on IFSG placed for a broad variety of indications. The primary end point was to determine the percentage of wounds closed at 32 weeks, and the secondary objective was to determine the median number of IFSG applications during this period. The registry was queried for patients who had IFSG placed for wounds created by Mohs surgery.
Results:
As of mid-April 2024, 41 participants enrolled in the registry had undergone placement of IFSG post-Mohs surgery. The mean (standard deviation) patient age was 77.6 (8.9) years, and 24% of participants were female (n = 10). Forty of 41 wounds (97.6%) achieved complete wound closure in a median of 5 weeks, and the median number of visits was 5. For closed wounds, the median number of applications was 2.
Conclusion:
This registry demonstrates that in a real-world setting, IFSG provides support to aid wound closure. In the post-Mohs setting, only 1 to 2 IFSG applications were required. This study demonstrates how IFSG can be a viable option for Mohs surgeons to consider in the reconstruction paradigm for a variety of wound sizes and anatomic locations.

