Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Soft part tumors.

H D Suit, W O Russell

    Cancer
    |February 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Pediatric rhabdomyosarcoma management has improved with a multimodal approach combining chemotherapy, radiation, and surgery. This comprehensive strategy significantly enhances local control and disease-free survival rates in children.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Chronic leptomeningitis and ependymitis caused by Ustilago, probably U. zeae (corn smut).

    The American journal of pathology·2010
    Same author

    Systemic nonlipoid reticulo-endothelial granuloma (Letterer-Siwe's type); a pathologic study of four cases.

    The American journal of pathology·2010
    Same author

    Congenital heart disease with necrotizing arteritis (periarteritis nodosa) limited to the pulmonary arteries; report of case with necropsy.

    The American journal of pathology·2010
    Same author

    [Fibrocaseous coccidioidomycosis with cavitation in the upper lobe in the right lung].

    California medicine·2010
    Same author

    Human toxoplasmosis; a clinicopathologic study with presentation of five cases and review of the literature.

    Medicine·2010
    Same author

    Primary Intracranial Chorionepithelioma with Metastases to the Lungs.

    The American journal of pathology·2009
    Same journal

    Toward exercise as standard care for older cancer survivors.

    Cancer·2026
    Same journal

    Maintenance therapy in gynecologic malignancies: Current and future state.

    Cancer·2026
    Same journal

    Long-term outcomes of evolving treatment regimens in Ewing sarcoma survivors diagnosed 1970-1999: A report from the Childhood Cancer Survivor Study.

    Cancer·2026
    Same journal

    Large-scale osteosarcoma sequencing reveals age-associated genomic architectures.

    Cancer·2026
    Same journal

    EZH2 inhibitor tazemetostat voluntarily withdrawn from market.

    Cancer·2026
    Same journal

    Nivolumab and chemotherapy combination approved for previously untreated Hodgkin lymphoma.

    Cancer·2026
    See all related articles

    Area of Science:

    • Pediatric Oncology
    • Surgical Oncology
    • Radiation Oncology

    Background:

    • Rhabdomyosarcoma outcomes have dramatically improved over the past decade.
    • A three-modality treatment approach combining chemotherapy, radiation, and surgery is key to these advancements.

    Purpose of the Study:

    • To present treatment outcomes for soft tissue sarcoma in pediatric patients.
    • To evaluate the efficacy of radical dose radiation therapy and limited surgery.
    • To analyze the impact of staging and treatment planning on patient survival.

    Main Methods:

    • Review of 100 pediatric soft tissue sarcoma patients treated with radiation and surgery.
    • Utilized a new American Joint Committee (AJC) staging system based on histopathological grade.
    • Assessed local control and disease-free survival rates in relation to stage and treatment modalities.

    Related Experiment Videos

    Main Results:

    • Outcomes correlated with advancing stage; anatomic site was not a significant factor.
    • Radical dose radiation therapy (less than 6300 rad) combined with limited surgery showed variable results.
    • Hypoxic radiation therapy under tourniquet did not significantly improve outcomes compared to conventional methods.

    Conclusions:

    • Multimodal therapy significantly improves outcomes for pediatric rhabdomyosarcoma.
    • Treatment planning must consider potential future surgical needs, optimizing radiation fields.
    • The AJC staging system is crucial for predicting treatment response and survival.