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Related Experiment Video

Updated: May 13, 2025

A Porcine Model of Acute Autologous Pulmonary Embolism

A Porcine Model of Acute Autologous Pulmonary Embolism

Published on: September 6, 2024

Risk factors for pulmonary embolism: a case-control study.

Geng Yang¹, Shaoping Nie²

¹Emergency Rescue Center, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.

Journal of Thoracic Disease

|April 14, 2025

Summary

Obstructive sleep apnea-hypopnea syndrome (OSAHS), hypertension, and smoking are significant risk factors for pulmonary embolism (PE). Lower arterial partial pressure of carbon dioxide (PCO2) may offer protection against PE.

Keywords:

Pulmonary embolism (PE)hypertension obstructive sleep apnea-hypopnea syndrome (OSAHS)risk factors smoking

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Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet

Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet

Published on: November 4, 2015

Area of Science:

Cardiology
Pulmonology
Epidemiology

Background:

Pulmonary embolism (PE) presents diagnostic challenges and carries a poor prognosis.
Identifying modifiable risk factors is crucial for improving patient outcomes.

Purpose of the Study:

To investigate modifiable risk factors associated with pulmonary embolism (PE).
To establish an age- and sex-matched case-control study design for PE risk factor analysis.

Main Methods:

A case-control study was conducted involving 129 PE patients and matched controls.
Clinical variables including hypertension, diabetes, BMI, smoking, SBP, and OSAHS were analyzed.
Conditional logistic regression was employed for multivariate analysis.

Main Results:

Obstructive sleep apnea-hypopnea syndrome (OSAHS), hypertension, and smoking were identified as independent risk factors for PE.
Triglycerides and estimated glomerular filtration rate (eGFR) showed no significant association with PE.
A negative correlation was observed between arterial partial pressure of carbon dioxide (PCO2) and PE risk.

Conclusions:

OSAHS, hypertension, and smoking are strongly linked to increased PE risk.
Arterial PCO2 may have a protective effect against the development of PE.
A validated risk model and scoring system for PE were developed.