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Updated: May 13, 2025
A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
Published on: February 2, 2021
Continuous renal replacement therapy for acute kidney injury: a case report
Jianmin Wang1, Yiyao Bao1, Lijun Guan1
1Department of Surgical ICU, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, China.
Insights
Pediatric trauma can cause acute kidney injury (AKI), a serious condition. Early recognition and prompt renal replacement therapy are crucial for managing AKI in children, improving outcomes.
Area of Science:
- Pediatric Nephrology
- Trauma Surgery
- Critical Care Medicine
Background:
- Acute kidney injury (AKI) is a significant complication in pediatric trauma patients.
- AKI in trauma is linked to multi-organ dysfunction and complex mechanisms.
- Close renal function monitoring is vital for severely injured children.
Observation:
- A 3-year-old boy experienced AKI after a car accident, leading to multi-organ dysfunction.
- The patient underwent laparotomy, liver repair, and received continuous renal replacement therapy (CRRT) for 7 days.
- Treatment included plasma exchange, antimicrobials, and multi-organ support.
Findings:
- The case highlights the need for rapid identification of traumatic AKI risk.
- Aggressive resuscitation strategies are essential for renal protection in trauma.
- Prompt initiation of CRRT can prevent adverse outcomes in severe AKI.
Implications:
- Improving early detection of traumatic AKI is critical.
- Proactive renal support strategies should be implemented in pediatric trauma care.
- This case underscores the importance of timely CRRT for pediatric AKI survivors.
Background:
Acute kidney injury is a severe complication of pediatric trauma with complex and diverse mechanisms and is associated with multiple organ dysfunction. For severely injured children, renal function should be closely monitored, and continuous renal replacement therapy should be promptly initiated if there is a risk of developing severe acute kidney injury. This case report describes the treatment process of a child with acute kidney injury due to trauma, highlighting the need to improve the rapid identification of traumatic acute kidney injury risk and actively implement resuscitation strategies to protect renal function in trauma patients.
Case Description:
A 3-year-old boy presented with acute kidney injury following a car accident. Multi-organ dysfunction developed, and laparotomy and liver laceration repair were performed. Continuous renal replacement therapy for 7 days, plasma exchange, antimicrobial therapy, and multi-organ support were provided. A 1-year follow-up showed no organ dysfunction.
Conclusions:
This case report describes the treatment process of a child with acute kidney injury due to trauma, highlighting the need to improve the rapid identification of traumatic acute kidney injury risk and actively implement resuscitation strategies to protect renal function in patients with trauma. Prompt continuous renal replacement therapy should be considered when necessary to prevent adverse outcomes.
