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Sleep Disturbance and Psychological Stress: Two Interconnected Conditions in Chronic Spontaneous Urticaria
Pinar Ozdemir Cetinkaya1, Birgul Ozkesici Kurt1, Ayberk Aktaran1
1Department of Dermatology and Venereology, University of Health Sciences Türkiye, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Türkiye.
Sisli Etfal Hastanesi Tip Bulteni
|April 14, 2025
Summary
Chronic spontaneous urticaria (CSU) significantly impacts mental health and sleep quality. Patients with CSU experience higher rates of depression, anxiety, and poor sleep compared to healthy individuals.
Area of Science:
- Dermatology
- Psychiatry
- Sleep Medicine
Background:
- Chronic spontaneous urticaria (CSU) is a prevalent skin condition causing wheals and angioedema.
- The chronic and itchy nature of CSU can significantly impair psychological well-being and sleep quality.
Purpose of the Study:
- To assess the impact of CSU on depression, anxiety, stress, and sleep quality.
- To investigate the relationship between these psychological factors and disease-specific parameters in CSU patients.
Main Methods:
- A prospective case-control study involving 86 CSU patients and 86 healthy controls.
- Utilized validated questionnaires: DASS-21 (Depression, Anxiety, Stress), PSQI (Sleep Quality), and DLQI/CU-Q2oL (Quality of Life).
- Recorded disease activity scores like UAS7.
Main Results:
- CSU patients exhibited significantly higher scores for depression, anxiety, stress, and poorer sleep quality compared to controls.
- A majority of CSU patients (79.1%) reported poor sleep quality.
- Worse sleep quality correlated with higher disease activity (UAS7) and poorer psychological status (depression, anxiety, stress, DLQI/CU-Q2oL).
Conclusions:
- CSU is associated with significant psychological distress and sleep disturbances.
- Healthcare providers should consider psychological comorbidities and sleep issues in CSU management.
- Addressing these factors can improve overall patient well-being.
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