Related Experiment Video

Updated: Jun 28, 2026

Passive Administration of Monoclonal Antibodies Against H. capsulatum and Others Fungal Pathogens
09:57

Passive Administration of Monoclonal Antibodies Against H. capsulatum and Others Fungal Pathogens

Published on: February 14, 2011

11.9K

Acute Myelopathy as Initial Presentation of Disseminated Histoplasmosis: A Case Report

Lisle Blackbourn1,2, Elisa Yoo3, Michael D Lunt4

  • 1Department of Neurology, University of Illinois College of Medicine Peoria, Peoria, Illinois, USA.

Case Reports in Infectious Diseases
|April 14, 2025
PubMed

Insights

This case study highlights a rare presentation of disseminated histoplasmosis in an immunocompromised patient, manifesting as acute thoracic myelopathy. Diagnosis was confirmed via biopsy, emphasizing the challenges in identifying this fungal infection.

Area of Science:

  • Mycology
  • Infectious Diseases
  • Neurology

Background:

  • Histoplasmosis, caused by *Histoplasma capsulatum*, is a fungal infection.
  • Central nervous system (CNS) involvement is rare but can present diversely, including meningitis, encephalitis, and lesions.
  • CNS histoplasmosis poses diagnostic challenges due to varied presentations and limited sensitive tests.
Keywords:
CNS histoplasmosisacute myelopathycase reportdisseminated histoplasmosisimmunocompromised

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