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Comparing Hospital-Free Days by Frailty Status for Patients Undergoing Surgical Intervention for Cardiovascular
Hasan Nassereldine1, Yekaterina Khamzina1, Jason Kennedy2
1From the Departments of Surgery (Nassereldine, Khamzina, Tzeng, Reitz), University of Pittsburgh, PA.
Frailty in surgical patients significantly impacts outcomes, reducing hospital free days (HFD) and increasing mortality risk. Hospital free days (HFD) offer a comprehensive measure for assessing patient recovery post-surgery.
Area of Science:
- Geriatric Surgery
- Patient Outcomes Research
- Health Services Research
Background:
- Aging populations present increased surgical complexity due to comorbidities like atherosclerotic cardiovascular diseases (ASCVD).
- Patient frailty is a significant predictor of adverse postoperative outcomes in surgical patients.
- Hospital free days (HFD) is a patient-centered metric quantifying time spent at home post-discharge.
Purpose of the Study:
- To assess the association between patient frailty and 90-day hospital free days (HFD-90).
- To evaluate the relationship between frailty and in-hospital mortality in surgical patients.
- To determine the utility of HFD-90 as a comprehensive outcome measure in frail surgical cohorts.
Main Methods:
- Retrospective analysis of 67,861 patients undergoing major cardiovascular surgeries (2015-2018) from the Florida State Inpatient Database.
- Frailty assessed using the Risk Analysis Index (RAI).
- Multivariable regression models (zero-inflated negative binomial and ordinal logistic) used to analyze HFD-90 and in-hospital mortality in relation to frailty status.
Main Results:
- Frail patients experienced significantly lower 90-day hospital free days (HFD-90) compared to normal patients (aRR=0.95).
- Frailty was strongly associated with a higher risk of in-hospital mortality (aOR=6.20) compared to robust or normal patients.
- Robust patients demonstrated increased HFD-90 (aRR=1.03) and decreased in-hospital mortality (aOR=0.40) compared to normal patients.
Conclusions:
- 90-day hospital free days (HFD-90) is a feasible and comprehensive patient-centered metric for evaluating surgical outcomes.
- HFD-90 effectively integrates key postoperative outcomes including mortality, length of stay, and readmission into a single measure.
- This metric is particularly valuable for assessing outcomes in frail surgical patient populations.
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