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Updated: May 5, 2026

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
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A Network-Based Approach Exploiting Transcriptomics and Interactomics Data for Predicting Drug Repurposing Solutions

Alessio Galimi1, Giulia Fiscon1,2

  • 1Department of Computer, Control, and Management Engineering "Antonio Ruberti", Sapienza University of Rome, 00185 Rome, Italy.

Cancers
|April 14, 2025
PubMed

Insights

Drug development is a lengthy process, taking 12-13 years from initial synthesis to market availability. This timeline highlights the significant investment and duration required for new medicines.

Area of Science:

  • Pharmaceutical Sciences
  • Medicinal Chemistry
  • Drug Development

Background:

  • The journey of a new drug from laboratory synthesis to patient accessibility is exceptionally long and complex.
  • The European Federation of Pharmaceutical Industries and Association (EFPIA) provides data on drug development timelines.

Purpose of the Study:

  • To elucidate the typical duration of the drug development process.
  • To highlight the key stages involved in bringing a new active substance to market.

Main Methods:

  • Analysis of industry data and reports.
  • Review of regulatory and pharmaceutical development pathways.

Main Results:

  • The average time for a drug to reach the market is approximately 12 to 13 years.
  • This timeline encompasses discovery, preclinical testing, clinical trials, and regulatory review.

Conclusions:

  • Drug development is a resource-intensive and time-consuming endeavor.
  • Understanding these timelines is crucial for pharmaceutical innovation and healthcare planning.
Keywords:
drug repurposingnetwork theorypathways analysis

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