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Updated: May 13, 2025

Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function
Published on: April 12, 2024
Ensembled YOLO for multiorgan detection in chest x-rays
Sivaramakrishnan Rajaraman1, Zhaohui Liang1, Zhiyun Xue1
1Division of Intramural Research, National Library of Medicine, National Institutes of Health, 8600 Rockville Pike, Bethesda, MD USA 20894.
This study introduces a multi-organ detection technique for Chest X-rays (CXRs) using You Only Look Once (YOLO) models. YOLOv9 demonstrated superior performance over YOLOv8 for simultaneous lung and heart detection, with ensemble methods further enhancing accuracy.
Area of Science:
- Medical Imaging
- Artificial Intelligence in Radiology
- Computer Vision
Background:
- Chest radiographs (CXRs) are crucial for diagnosing thoracic pathologies.
- AI/ML applications in CXR analysis require precise anatomical structure detection.
- Current object detection models like YOLO excel at single organ detection but lack multi-organ capabilities.
Purpose of the Study:
- To develop and evaluate a multi-organ detection technique for simultaneous lung and heart identification in CXRs.
- To compare the performance of recent YOLO versions (YOLOv8 and YOLOv9) and their sub-variants for this task.
- To assess the generalizability of the proposed models using external datasets.
Main Methods:
- Implementation of multi-organ detection using two recent YOLO versions and their sub-variants.
- Training and internal validation on the JSRT CXR dataset.
- External evaluation on the Montgomery CXR and RSNA CXR datasets.
- Ensemble approaches were explored to improve detection performance.
Main Results:
- YOLOv9 models significantly outperformed YOLOv8 variants in simultaneously detecting lung and heart regions.
- The proposed multi-organ detection technique demonstrated effectiveness on both internal and external datasets.
- Ensemble methods further improved the detection accuracy.
Conclusions:
- YOLOv9 offers a robust solution for multi-organ detection in CXR images.
- The developed technique advances AI-driven medical image analysis for improved diagnostic capabilities.
- Simultaneous multi-organ detection in CXRs is feasible and beneficial for clinical applications.
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