Inflammation Diet and the Association with Inflammatory Markers in Individuals with Obesity - A Systematic Scoping...

This review examines the relationship between diet-induced inflammation and inflammatory markers in obese individuals. Considering the chronic inflammatory state linked to obesity and its association with metabolic diseases, the review focuses on how dietary patterns, particularly pro- and anti-inflammatory patterns, impact inflammation.

Recent studies suggest that pro-inflammatory diets, rich in processed and energy-dense foods, are associated with elevated levels of inflammatory markers, such as C-reactive protein and interleukin-6, in individuals with obesity. Using the Dietary Inflammatory Index (DII), research has found correlations between high DII scores and increased levels of inflammation. However, results regarding other biomarkers like TNF-alpha, leptin, and adiponectin are mixed. Adopting an anti-inflammatory diet - rich in fiber, omega-3 fatty acids, and polyphenols while low in processed foods and refined sugars -may reduce inflammation markers. However, the extent of these effects varies across studies, populations, and methods, highlighting the heterogeneity of the findings. Diet is a modifiable factor in managing obesity-related inflammation. While pro-inflammatory diets consistently elevate inflammatory biomarkers, anti-inflammatory diets show potential benefits but inconsistent results. The DII is a valuable tool, but further research is needed to clarify its role in managing inflammation and supporting long-term health, considering factors like physical activity and body composition.