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Global Trends in CD4 Measurement and Immunosuppression at ART Initiation Among Children With HIV
Gabriela Patten1, Karen Malateste2, Carolyn Bolton Moore3
1From the Centre for Infectious Disease Epidemiology and Research, University of Cape Town, Cape Town, South Africa.
The Pediatric Infectious Disease Journal
|April 15, 2025
Abstract
None:
Eligibility for antiretroviral therapy is no longer based on immune criteria. In a global cohort of 97,453 children, between 2005 and 2021, we observed large declines in CD4 measurement, from 51% to 12% among <5 seconds, and from 74% to 20% among those 5-14 years of age. Lack of CD4 testing may negatively affect clinical care and surveillance of severe immune suppression.
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