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Related Concept Videos

Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

68
The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
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Appendicitis-II: Diagnostic Studies and Management01:29

Appendicitis-II: Diagnostic Studies and Management

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Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
52
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

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Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
129
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

325
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
325
Other Disorders of Digestive System01:30

Other Disorders of Digestive System

596
The gastrointestinal tract is susceptible to various disorders. If the lower esophageal sphincter is damaged, stomach acid can flow back into the esophagus, causing irritation and inflammation of the lining. This condition is called gastroesophageal reflux disease (known as heartburn) and may cause chest pain and difficulty swallowing. In the stomach, prolonged use of nonsteroidal anti-inflammatory drugs like aspirin, chronic alcohol consumption, bacterial infections such as Helicobacter...
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Gastritis III: Clinical Manifestations and Management01:23

Gastritis III: Clinical Manifestations and Management

101
The clinical manifestations of gastritis can vary depending on the cause and type of gastritis, but some common symptoms may include the following.
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
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Related Experiment Video

Updated: May 13, 2025

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch
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Gastrointestinal Behҫet's disease mimicking appendicitis.

Evan Manning1, Erica M Hill2, Amy Jiang3

  • 1Rheumatology, Brooke Army Medical Center, Fort Sam Houston, Texas, USA Evan.P.Manning.mil@Health.mil.

BMJ Case Reports
|April 15, 2025
PubMed
Summary

Behçet's disease can mimic appendicitis, leading to misdiagnosis. A colonoscopy revealed ileocecal Behçet's disease, preventing unnecessary surgery and confirming the need for steroid treatment.

Keywords:
Crohn's diseaseEndoscopyGastrointestinal surgeryInflammatory bowel diseaseVasculitis

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Area of Science:

  • Gastroenterology
  • Rheumatology
  • Internal Medicine

Background:

  • Behçet's disease is a rare multisystem inflammatory disorder.
  • Abdominal pain is a common manifestation, often mimicking surgical emergencies like appendicitis.
  • Immunosuppressive therapy in Behçet's disease can alter disease presentation.

Purpose of the Study:

  • To highlight the diagnostic challenge of differentiating Behçet's disease flare from appendicitis.
  • To emphasize the utility of colonoscopy in diagnosing gastrointestinal Behçet's disease.
  • To illustrate the successful management of Behçet's disease presenting as appendicitis.

Main Methods:

  • Case report of a patient with a history of Behçet's disease presenting with abdominal pain.
  • Initial diagnostic workup included CT scan, suggesting appendicitis.
  • Subsequent diagnostic evaluation involved colonoscopy to assess for gastrointestinal pathology.

Main Results:

  • CT scan findings were consistent with appendicitis.
  • Colonoscopy revealed aphthous ulcers, a large cecal ulcer, and appendiceal orifice inflammation, indicative of ileocecal Behçet's disease.
  • Treatment with systemic glucocorticoids led to complete symptom resolution.

Conclusions:

  • Behçet's disease can present with symptoms mimicking acute appendicitis.
  • Colonoscopy is crucial for accurate diagnosis in such cases, potentially avoiding unnecessary surgery.
  • Prompt recognition and appropriate immunosuppressive therapy (glucocorticoids) are vital for managing gastrointestinal Behçet's disease flares.