Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

MicroRNAs01:22

MicroRNAs

21.0K
MicroRNA (miRNA) are short, regulatory RNA transcribed from introns—non-coding regions of a gene—or intergenic regions—stretches of DNA present between genes. Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After...
21.0K
Transgenic Plants02:50

Transgenic Plants

7.0K
Recombinant DNA technology called transgenesis is often used to add a foreign gene or remove a detrimental gene from an organism. Such genetically modified organisms are called transgenic organisms.
The first-ever transgenic plant was a tobacco plant developed in 1983 that showed resistance against the tobacco mosaic virus. Since then, many transgenic plants have been developed and commercialized for improving the agricultural, ornamental, and horticultural value of a crop plant. Transgenic...
7.0K
Experimental RNAi02:15

Experimental RNAi

6.0K
RNA interference (RNAi) is a cellular mechanism that inhibits gene expression by suppressing its transcription or activating the RNA degradation process. The mechanism was discovered by Andrew Fire and Craig Mello in 1998 in plants. Today, it is observed in almost all eukaryotes, including protozoa, flies, nematodes, insects, parasites, and mammals. This precise cellular mechanism of gene silencing has been developed into a technique that provides an efficient way to identify and determine the...
6.0K
piRNA - Piwi-interacting RNAs02:57

piRNA - Piwi-interacting RNAs

6.7K
PIWI-interacting RNAs, or piRNAs, are the most abundant short non-coding RNAs. More than 20,000 genes have been found in humans that code for piRNAs while only 2000 genes have been found for miRNAs. piRNAs can act at the transcriptional and post-transcriptional levels and have a vital role in silencing transposable elements present in germ cells. They are also involved in epigenetic silencing and activation. Previously, they were thought to function only in germ cells but new evidence suggests...
6.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Spatial transcriptomics on an expanded dataset at the brain-electrode interface: exploration of variability and identification of novel biomarkers.

Frontiers in neuroscience·2026
Same author

Molecular Interplay of PARN and Telomerase: Tail Modifiers and Disease Implications.

Wiley interdisciplinary reviews. RNA·2026
Same author

Correction: F2,6BP restores mitochondrial genome integrity in Huntington's disease.

The Journal of biological chemistry·2026
Same author

Breed-specific transcriptomic pathways underpin seasonal cold exposure responses in indigenous and crossbred cattle.

Tropical animal health and production·2026
Same author

Realization of a spin glass in a two-dimensional van der Waals material.

Science (New York, N.Y.)·2026
Same author

Retraction Note: Transgenic expression of an unedited mitochondrial orfB gene product from wild abortive (WA) cytoplasm of rice (Oryza sativa L.) generates male sterility in fertile rice lines.

Planta·2026

Related Experiment Video

Updated: May 13, 2025

Potato Virus X-Based microRNA Silencing VbMS In Potato.
11:51

Potato Virus X-Based microRNA Silencing VbMS In Potato.

Published on: May 11, 2020

3.1K

Delineating microRNA169-Nuclear Factor Y-Subunit A Module for Its Potential Implications in Crop Improvement.

Anirban Chakraborty1, Shambhavi Sharma2, Girdhar K Pandey1

  • 1Department of Plant Molecular Biology, University of Delhi, South Campus, New Delhi, India.

Plant, Cell & Environment
|April 16, 2025
PubMed
Summary
This summary is machine-generated.

The miR169-NFYA network regulates plant development and stress responses. Understanding this network is key to developing climate-resilient crops with improved productivity for global food security.

Keywords:
NFYAfeedback regulationmiR169salt toleranceseed traitsviral defense

More Related Videos

RNA Blot Analysis for the Detection and Quantification of Plant MicroRNAs
14:41

RNA Blot Analysis for the Detection and Quantification of Plant MicroRNAs

Published on: July 11, 2020

10.5K
mirMachine: A One-Stop Shop for Plant miRNA Annotation
06:16

mirMachine: A One-Stop Shop for Plant miRNA Annotation

Published on: May 1, 2021

2.4K

Related Experiment Videos

Last Updated: May 13, 2025

Potato Virus X-Based microRNA Silencing VbMS In Potato.
11:51

Potato Virus X-Based microRNA Silencing VbMS In Potato.

Published on: May 11, 2020

3.1K
RNA Blot Analysis for the Detection and Quantification of Plant MicroRNAs
14:41

RNA Blot Analysis for the Detection and Quantification of Plant MicroRNAs

Published on: July 11, 2020

10.5K
mirMachine: A One-Stop Shop for Plant miRNA Annotation
06:16

mirMachine: A One-Stop Shop for Plant miRNA Annotation

Published on: May 1, 2021

2.4K

Area of Science:

  • Plant molecular biology
  • Genetics
  • Crop science

Background:

  • Climate change negatively impacts plant growth and productivity.
  • Feeding a growing global population requires climate-resilient crops.
  • Understanding plant regulatory pathways is crucial for crop improvement.

Purpose of the Study:

  • To provide an exhaustive compilation of regulatory pathways influenced by the miR169-NFYA network in plants.
  • To elucidate the role of miR169 in post-transcriptionally regulating NFYA transcription factors.
  • To identify downstream components of the miR169-NFYA cascade.

Main Methods:

  • Literature review and compilation of existing studies on the miR169-NFYA network.
  • Analysis of molecular signatures related to plant development and stress responses.
  • Identification of key biological processes regulated by miR169-NFYA.

Main Results:

  • The miR169-NFYA network impacts multiple plant biological processes.
  • NFYA transcription factors regulate genes involved in development and stress.
  • miR169 post-transcriptionally suppresses NFYA expression.
  • Downstream pathways include hormone signaling, calcium signaling, epigenetics, nutrient starvation, and miRNA biogenesis.

Conclusions:

  • The miR169-NFYA nexus is a critical regulatory hub in plants.
  • This network offers a promising target for genetic manipulation to enhance crop resilience and productivity.
  • Targeting miR169-NFYA can contribute to developing climate-resilient crop varieties.