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Updated: May 13, 2025

Parallel Measurement of Circadian Clock Gene Expression and Hormone Secretion in Human Primary Cell Cultures
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Parallel Measurement of Circadian Clock Gene Expression and Hormone Secretion in Human Primary Cell Cultures

Published on: November 11, 2016

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DEC1 Regulates Human β Cell Functional Maturation and Circadian Rhythm

Sam Preza, Bliss Zheng, Zihan Gao

    Biorxiv : the Preprint Server for Biology
    |April 16, 2025
    PubMed
    Summary

    A key protein, DEC1, is crucial for maturing stem cell-derived islet organoids for diabetes therapy. It ensures proper insulin release and glucose response, vital for functional cell replacement.

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